Platelet Rich Fibrin (PRF) Bio Filler Gel

Aleksandra Predota, Board-Certified APRN FNP-C in Middletown, RI

Why choose Scientiphika Medical Spa
for your PRF Bio Filler procedure?

What is Platelet Rich Fibrin (PRF) Bio Filler gel?

Platelet Rich Fibrin Bio Fillers with plasma gel is a ground-breaking regenerative procedure used to restore youthfulness to your face, neck, or hands. They are fillers that use your plasma.

Our Medical Director and Board-Certified APRN, FNP-C Aleksandra Predota prepares the filler and treats your volume loss during the same appointment. Bio-filler using plasma gel is an “autologous aesthetic procedure”, which means that the product involved uses the patient’s own cells or tissue. The gel is mixed with your blood and then injected to restore volume loss.

The plasma gel adds plumpness to areas with lost volume while smoothing the appearance of fine lines and wrinkles. After treatment, our patients share they look and feel refreshed and revitalized. Platelet Rich Fibrin Bio Fillers use a gel derived from your own blood, helping to eliminate the risk of side effects such as rejection of the filler.

Vegan and allergy suffer clients find this procedure an exciting advancement.

How does the PRF Bio Filler work?

Fibrin is a biological scaffold that forms in response to an injury anywhere in the body. Platelets circulating in the blood will bind to a scaffold of fibrin. When platelets bind to the fibrin scaffold, they become activated and release growth factors, which start the wound healing process by creating new skin cells, collagen and blood vessels. By injecting PRF into an area on the face or scalp, a controlled inflammatory response is created, which kick starts new cell growth and collagen production.

What areas does the PRF Bio Filler treat?

Initially, you will experience swelling in the treatment area, that can last up to a week.  The swelling is the first step in treating the age-related volume loss, which causes fine lines and wrinkles. As the swelling subsides, the volume restoration softens and diminishes wrinkles. Immediately after the treatment, you will see an improvement in volume loss and an increase in collagen production starting in the weeks thereafter. Within a couple of months, the gel becomes naturally and wholly absorbed into the treatment area.

What can I expect to experience after my treatment?

Initially, you will experience swelling in the treatment area, that can last a few days. The swelling is the first step in treating the age-related volume loss, which causes fine lines and wrinkles. As the swelling subsides, the volume restoration softens and diminishes wrinkles. Immediately after the treatment, you will see an improvement in volume loss and an increase in collagen production starting in the weeks thereafter. Within a couple of months, the gel becomes naturally and wholly absorbed into the treatment area.

Experience EZPRF skin rejuvenation therapy in Middletown ,RI

The use of blood concentrates is becoming more and more popular in medical aesthetics.

Patients like the idea of using their own cells instead of a synthetic alternative in their quest for a younger and fresher look. EZ PRF is a blood concentration that is a result of years of experience and study. Not only does EZPRF contain more platelets per mcL, it also has leukocytes (WBC) and mesenchymal stem cells.

What makes ezPRF better than traditional PRP or PRFM?
FAQ's
How long does the Platelet Rich Fibrin Bio Filler treatment take?

The procedure lasts around 90 mins.

Who are the patients that benefit from this procedure?

Platelet Rich Fibrin Bio Fillers are an excellent choice for both men and women of various ages. Results are long-lasting and natural. It is often an ideal aesthetic treatment for vegans or allergy sufferers.

During Your Appointment

During the appointment, Aleksandra will take between 20 ml to 60 ml of your blood, which is spun is a centrifuge and processed to create the Platelet Rich Fibrin and then the Bio Filler. She injects this bio filler to treat volume loss.

Is there any downtime?

There is typically no downtime.

Is the treatment painful?

A few minor injections result in minor discomfort, but otherwise the treatment is completely non-invasive and painless. 

How many treatments are needed?

Typically, a treatment course consists of three sessions over a three-month period.

Patients share that their results last for about two years.

What types of skin issues can PRF Bio Fillers treat?


  • Fine lines and wrinkles


  • Structural skin lifting


  • Skin areas that have lost volume


  • Ideal aesthetic treatment for vegans or allergy suffers
When will you begin observing results?

Immediately after your first treatment, and the effects of the collagen production happen over the following weeks. After two months, the gel becomes naturally and wholly absorbed into the treated area.